People
Principal Investigator |
Tim Elston |
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Graduate Students |
 Keith BreauCellBiology & Physiology Graduate Student kbro9@email.unc.edu I am interested in stem cell differentiation, cell polarity, and collective migration. I study the human intestinal epithelium, where a dedicated pool of rapidly-dividing stem cells transition into migrating differentiated cells in one of the most expansive examples of directed collective cell migration in the adult body. Read more…. |
 Elizabeth DavisBCB Graduate Student emae@med.unc.edu Cell migration is a crucial aspect of many biological processes. External signaling guides cells through the detection of stimuli in the extracellular matrix (ECM) that influences their movement. The method of guided cell migration that I am studying is durotaxis, where cells preferentially move towards stiffer regions of the ECM where they are guided by local protrusions called pseudopods. Read more…. |
Saygin Gulec I study GTPases and how the feedback loops they participate in result in spatiotemporal patterns that lead to the emergence of complex cellular behaviors. One of these behaviors is the formation of podosomes during phagocytosis. I use novel biosensors developed in collaborating labs to track the activity of individual GTPase molecules and use this data to build mathematical models that helps us analyze |
Grace Mclaughlin Filamentous growing fungi can contain hundreds to millions of nuclei within a single cell. In our model organism Ashbya gossypii, nuclei residing within a shared cytosol divide asynchronously from one another. Despite this nuclear autonomy, these large cells also tightly regulate the number of nuclei per unit cell volume. |
 Nathan SmyersBCB Graduate Student smyersn@email.unc.edu Cell signaling is governed by complex networks of biochemical interactions. These networks are critical for a wide range of cellular functions, from detecting environmental changes to cellular motility. Modeling signaling with reaction-diffusion equations (RDEs) requires prior knowledge Read more… |
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Postdoctoral Fellows
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Undergrads
Noah Shaul Undergraduate Student |
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 Sandy HahnResearch Associate sshahn@email.unc.edu |
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Alumni |
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