Saygin Gulec

Saygin Gulec
BCB Graduate Student
sayging@live.unc.eduI

I study GTPases and how the feedback loops they participate in result in spatiotemporal patterns that lead to the emergence of complex cellular behaviors. One of these behaviors is the formation of podosomes during phagocytosis. I use novel biosensors developed in collaborating labs to track the activity of individual GTPase molecules and use this data to build mathematical models that helps us analyze and understand the regulatory reaction network that gives rise to such behaviors.